It’s no secret that the Seattle Seahawks have the deadliest one-two punch in the NFL at interior tackle, and that it forms the foundation of their elite defense

This will be the second start for Philip Rivers for the Colts after he almost won at Seattle last week. The 49ers are 10-4 and pushing for a playoff spot. They blew out Tennessee last week, but the defense wasn't great. It won't matter as the 49ers will limit Rivers and Brock Purdy will play well. The 49ers keep on winning.

Even with some blips on the radar recently, Sam Darnold's first season with the Seattle Seahawks is being positively received by other organizations in the NFL.

Seattle is a massive home favorite, given that the Colts will be starting a 44-year-old coming off the couch. Indianapolis wins in just 21% of the model's simulations, which offers notable value for the +700 Colts money line. Indy covers the big spread in 56% of the sims and the Over hits 59% of the time.

Expert recap and game analysis of the Seattle Seahawks vs. Indianapolis Colts NFL game from December 14, 2025 on ESPN.

The Seahawks can clinch a spot in the 2026 NFL Playoffs with a win over the Rams on Week 16 Thursday Night Football