Biliary atresia (BA) represents one of the leading causes of pediatric liver failure, often requiring surgical intervention or transplantation in early infancy. Although traditionally viewed as an ...

PHOENIX — Seladelpar, a first-in-class, selective peroxisome proliferator-activated receptor delta agonist, shows significant improvement across key pruritus outcomes in patients with primary biliary ...

Editor’s note: This is an automatically generated transcript. Please notify [email protected] if there are concerns regarding accuracy of the transcription. A number of new treatments have become ...

Primary biliary cholangitis (PBC) has typically been considered a rare condition, with a pooled global estimated incidence of two per 100,000 people per year and an estimated prevalence of 15 per ...

Biliary atresia is a rare liver disease where bile ducts become blocked, leading to rapid liver damage in infants. Early diagnosis, ideally within the first 60 days of life, is the single most ...

Once clinical suspicion has been established for primary biliary cholangitis (PBC), the "serologic hallmark" of the autoimmune disease are anti-mitochondrial antibodies (AMA), present in approximately ...

Neonatal hepatitis (NH) and biliary atresia are two separate conditions that share specific symptoms. Both conditions affect newborn infants and can cause liver damage. Bile is a substance the liver ...

Inflammation and scarring of the bile ducts—also known as cholangiopathies—can stop the bile from flowing, a vital fluid that helps digest fats. When bile can’t move through these ducts, it backs up ...

An expert explains what biliary tract cancers are and the current landscape of treatment as well as future advancements. In the treatment of newly diagnosed biliary tract cancer, the current standard ...

The strategy includes examination of infant eye color, stool color, and prior laboratory results to assess whether drawing a direct or conjugated bilirubin level is warranted. HealthDay News — In a ...

Livdelzi (seladelpar) is a medicine that can treat primary biliary cholangitis (PBC) by reducing the amount of bile in your body. It does this by signaling the body to stop making bile acid. People ...