Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

As antibiotic-resistant infections rise and are projected to cause up to 10 million deaths per year by 2050, scientists are looking to bacteriophages, viruses that infect bacteria, as an alternative.

D microscopy shows that the giant bacterium Thiovulum imperiosus squeezes its DNA into peripheral pouches, not a central mass ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

This valuable descriptive manuscript builds on prior research showing that the elimination of Origin Recognition Complex (ORC) subunits does not halt DNA replication. The authors obtain solid data ...

The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...