Zenas anticipates submitting a Biologics License Application (BLA) to the FDA in the second quarter of 2026 and a Marketing ...

Objectives The European Alliance of Associations for Rheumatology (EULAR) recommendations for the management of systemic lupus erythematosus (SLE) and lupus nephritis provide important guidance for ...

Adjunctive glucocorticoids may reduce mortality among patients with severe community-acquired pneumonia (CAP) in well-resourced settings. Whether these drugs are beneficial in low-resource settings ...

A team from the UB has described for the first time the molecular self-assembly process of this key protein and has revealed how its active conformation differs from the traditional model accepted for ...

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR). This essential protein ...

Valacyclovir is a generic prescription oral tablet used to treat herpes simplex infections. Its mechanism of action is to make it harder for the herpes virus to multiply. The herpes virus spreads in ...

Glucocorticoids represent the most potent class of anti-inflammatory drugs. However, their anti-inflammatory mode of action has been incompletely understood. Recent insights have revealed a key role ...

4 University Hospital Essen and University of Duisburg-Essen, Institute of Physiology, Essen, Germany 5 University of Erlangen-Nuremberg, Institute of Experimental and Clinical Pharmacology and ...

More than 44% of individuals receiving high doses of prolonged glucocorticoid medication develop osteonecrosis, with the femoral head being the most commonly affected site, predominantly in those aged ...

Jeremy has more than 2200 published articles on Collider to his name, and has been writing for the site since February 2022. He's an omnivore when it comes to his movie-watching diet, so will gladly ...

Glucocorticoids are steroid hormones that regulate multiple physiological processes throughout the lifespan and play a central role in the adaptive stress response. Their biological effects are ...

Both renal response and low disease activity independently predicted earlier glucocorticoid discontinuation in patients with lupus nephritis. A 10-year prospective study identified predictors and ...