Tight junctions, also known as zonulae occludentes, are the most apical of the cell-to-cell junctions in epithelial and endothelial cells. They form a continuous belt-like seal around cells, ...

Abstract: Intercellular communication is an important target for drug development. Although artificial lipid bilayers have been used for studying functions of various membrane proteins, there is a ...

Mutations in the desmosomal protein plakoglobin cause arrhythmogenic right ventricular cardiomyopathy (ARVC). These mutations likely alter intercellular adhesion and impair cellular responses to ...

The interaction between Hertwig's epithelial root sheath (HERS) and surrounding mesenchymal cells is crucial for root dentin formation. HERS influences tooth root development and odontoblast ...

Department of Biological Sciences, Indian Institute of Science Education And Research Kolkata, Mohanpur, India Chemical Engineering Department, University of Pittsburgh, Pittsburgh United States The ...

Intercellular forces generate distinct patterns of extrusion: high compressive forces (top panel) drive apoptotic cell extrusion toward the upper side, while lower compressive forces (bottom panel) ...

Most nervous systems combine both transmitter-mediated and direct cell–cell communication, known as ‘chemical’ and ‘electrical’ synapses, respectively. Chemical synapses can be identified by their ...

Adjacent cells freely exchange small molecules and ions with each other through channels made from proteins called connexins. Dysfunction in this important type of intercellular communication has been ...

Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication. Researchers have gained new knowledge of how drugs bind to connexin molecules. These ...

Abstract: Summary form only given. The barrier system of the skin not only defends against antigens and harmful substances, but also hinders the permeation of medicines and cosmetics into the dermis.