An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time in patients with advanced breast cancer, according to a study led by investigators ...

T cell lymphomas are notoriously difficult to treat because immunotherapy, despite being one of the most effective therapies for treating cancer, can't easily distinguish cancerous T cells from ...

New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane region ...

Imagine your immune cells could be modified to attack any kind of cancer. T cell receptor (TCR) therapy has the potential to one day become a universal cancer treatment. But there are risks.

A single receptor in blood vessels can trigger either harmful inflammation or protective healing, but scientists have struggled to understand how this is possible. UC San Diego researchers revealed ...

Taste, pain, or response to stress -- nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers have uncovered the ...

Pathogens can create sticky situations. When microbes invade the body to cause an infection, often one of their first lines of attack is to cling tenaciously to the surfaces of targeted human cells.

An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time in patients with advanced breast ...

Wistar Institute scientists have designed a two-vaccine approach that not only targets the tumors’ unique molecular identity ...

Adhesion G protein-coupled receptors have a large extracellular region (shown in green and orange) that extends into space outside the cell. Almost 35% of drugs approved by the Food and Drug ...