On Saturday, April 5, the actor, 48, reunited with Kerr Smith for a Dawson's Creek panel at Steel City Con in Pittsburgh, where they shared memories from their time on the set of the beloved '90s show. At one point, Van Der Beek recalled the exact moment when he realized that Dawson's Creek was going to change his career — and life — forever.

Busy Philipps is giving fans hope for a 'Dawson's Creek' reunion in support of James Van Der Beek after his colorectal cancer diagnosis.

Actress Michelle Williams, who played Jen on the WB show for its entire run from 1998 to 2003, was recently asked if she was in touch with her costar, actor James Van Der Beek, since he was diagnosed with colorectal cancer.