Amid a handful of injuries in their running back room, the San Francisco 49ers are bolstering their backfield.

The San Francisco 49ers preseason slate opens Saturday evening against the Denver Broncos at Levi's Stadium.

The San Francisco 49ers could use more capable running backs on their roster and signing Jeff Wilson Jr. gives them another.

The San Francisco 49ers cannot last more than a few months without losing their entire running back room to injury, even in the preseason. With multiple key players back on the shelf, the 49ers added ...

The San Francisco 49ers entered Saturday's game with just four running backs, and they lost one of them in the third quarter.

The San Francisco 49ers added some running back depth to their roster ahead of their preseason opener vs. the Denver Broncos.

The San Francisco 49ers are reuniting with former running back Jeff Wilson on a one-year deal, according to a report from ESPN's Adam Schefter. This is Wilson's second stint with the franchise. He ...

The 49ers scored a touchdown on their opening series of the preseason, then their defense crumbled in a 30-9 loss against the ...

The San Francisco 49ers signed running back Ke’Shawn Vaughn to a one-year deal ahead of their first preseason game against the Denver Broncos. Vaughn signed with the 49ers’ practice squad in August ...

San Francisco, who has battled numerous injuries on both sides of the ball throughout training camp, will re-sign former ...

The good news? Very few of the San Francisco 49ers' starters played in the first preseason game. The bad news? Those who ...