1 Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia Lower motor neuron (LMN) syndromes typically present with muscle wasting and weakness and ...

Dr Marina A J Tijssen, MRC Human Movement and Balance Unit, Institute of Neurology, Queen Square, London WC1N 3BG, UK. email M.Koning-Tijssen{at}ion.ucl.ac.uk Three cases of late onset Gilles de la ...

Correspondence to Dr Christine Lo, Department of Clinical Neurosciences, University of Oxford Nuffield, Oxford OX1 1NF, Oxfordshire, UK; christine.lo{at}nhs.net Background An unmet need remains for ...

a Department of Neurosurgery, Benjamin Franklin Medical Center, Free University of Berlin, Hindenburgdamm 30, 12200 Berlin, Germany, b Department of Radiology Dr Ruediger Stendel, Department of ...

Objective The Tysabri Observational Programme (TOP), which began >10 years ago, is an open-label, multinational, prospective observational study evaluating the long-term safety and effectiveness of ...

Institute for Neuroradiology, JW Goethe-University Frankfurt am Main, Frankfurt, Germany Dr Oliver Singer, Department of Neurology, JW Goethe-University Frankfurt am Main, Schleusenweg 2-16, D-60528 ...

Objectives The placement of an external ventricular drain (EVD) is a common neurosurgical operation that carries great benefit in acute hydrocephalus but is not without risk. In our centre, bolt EVDs ...

Anxiety is an adaptive response that promotes harm avoidance, but at the same time excessive anxiety constitutes the most common psychiatric complaint. Moreover, current treatments for anxiety—both ...

Background To evaluate the efficacy of rituximab in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) patients not responding to conventional immune therapies. Methods An open-label, ...

Correspondence to Dr Masaaki Niino, Department of Clinical Research, National Hospital Organization Hokkaido Medical Center, Sapporo 063-0005, Japan; niino.masaaki.tc{at}mail.hosp.go.jp Neuromyelitis ...

Objective It has been debated whether the different clinical disease courses in multiple sclerosis (MS) are the consequence of different pathogenic mechanisms, with distinct risk factors, or if all MS ...